An overview of chikungunya virus infection

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An overview of chikungunya virus infection

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Laboratory of Virology, "L. The main vectors are mosquitoes from the Aedes species. Recently, the establishment of an envelope mutation increased infectivity for A. CHIKV has recently re-emerged causing millions of infections in countries around the Indian Ocean characterized by climate conditions favourable to high vector density.

Importation of human cases to European regions with high density of suitable arthropod vectors such as A. The clinical signs of CHIKV infection include non-specific flu-like symptoms, and a characteristic rash accompanied by joint pain that may last for a long time after the resolution of the infection.

The death rate is not particularly high, but excess mortality has been observed in concomitance with large CHIKV outbreaks. Deregulation of innate defense mechanisms, such as cytokine inflammatory response, may participate in the main clinical signs of CHIKV infection, and the establishment of persistent chronic disease.

An overview of chikungunya virus infection

There is no specific therapy, and prevention is the main countermeasure. Prevention is based on insect control and in avoiding mosquito bites in endemic countries.

Diagnosis is based on the detection of virus by molecular methods or by virus culture on the first days of infection, and by detection of an immune response in later stages.

Differential diagnosis should take into account the cross-reactivity with other viruses from the same antigenic complex i.Chikungunya virus infection: an overview Claudia Caglioti, Eleonora Lalle, Concetta Castilletti, Fabrizio Carletti, Maria Rosaria Capobianchi, Licia Bordi Laboratory of Virology, “L.

Spallanzani” National Institute for Infectious Diseases, Rome, Italy. Chikungunya is an infection caused by the chikungunya virus (CHIKV). Symptoms include fever and joint pain. These typically occur two to twelve days after exposure. Other symptoms may include headache, muscle pain, joint swelling, and a rash.


Most people are better within a week; however, occasionally the joint pain may last for months. Infection by chikungunya virus is characterized mainly by fever, joint pain with or without swelling, and rash. In some infections, chronic arthritis results and has a debilitating effect.

Chikungunya fever, for which there is no cure or vaccine, is a viral infection. The chikungunya virus (CHIKV) is a member of the Togaviridae family and is part of the alphavirus genus. 1 It is an enveloped positive-strand RNA virus that has a kb genome. Chikungunya Virus.

Chikungunya virus is the cause of an ongoing epidemic in India and the islands of the southwest Indian Ocean (e.g., Reunion).

In India, million cases were reported in 75,76 Infection may cause uveitis with presentation several weeks after the acute febrile illness.

The most common eye findings are anterior uveitis . Dec 16,  · Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus belonging to the Togaviridae family, first isolated in Tanzania in The main vectors are mosquitoes from the Aedes species.

An overview of chikungunya virus infection

The main vectors are .

Chikungunya virus infection: an overview. - PubMed - NCBI